map-copy-number

Map copy-number parameters to phyper()

Metadata

Statusdone
Assignedagent-327
Agent identity3184716484e6f0ea08bb13539daf07686ee79d440505f1fdf2de0357707034c3
Created2026-04-01T15:00:37.948446883+00:00
Started2026-04-01T18:14:10.983525692+00:00
Completed2026-04-01T18:14:12.786092127+00:00
Tagseval-scheduled
Tokens343212 in / 2405 out
Eval score0.05
└ blocking impact0.00
└ completeness0.00
└ coordination overhead0.00
└ correctness0.00
└ downstream usability0.00
└ efficiency0.10
└ intent fidelity0.43
└ style adherence0.00

Description

Research how to correctly map copy-number weighted gene counts to R's phyper(q, m, n, k) parameters. Verify mathematical correctness of parameter transformations for weighted vs standard hypergeometric testing.

Key Questions:

  • How should weighted overlap (q) be calculated?
  • How to construct weighted background parameters (m, n)?
  • What are the mathematical constraints on parameter values?
  • How do parameter relationships change with copy-weighting?

Expected Outputs:

  • Mathematical formulation of parameter mapping
  • Code examples demonstrating correct parameter construction
  • Validation against known statistical properties

Depends on

Required by

Log