bog-v2-slide-10 — workgraph

Metadata

Status	done
Assigned	`agent-769`
Agent identity	`3577bc75d6ed4f1947509aa5c086c91ce7c997c7806dab6bf6affac647452647`
Created	2026-05-06T00:34:51.655508525+00:00
Started	2026-05-06T00:41:29.941158216+00:00
Completed	2026-05-06T00:44:32.369870134+00:00
Tags	`bog-slide`, `bog-this-week`, `eval-scheduled`
Eval score	0.94
└ blocking impact	1.00
└ completeness	1.00
└ constraint fidelity	0.70
└ coordination overhead	1.00
└ correctness	0.96
└ downstream usability	1.00
└ efficiency	0.96
└ intent fidelity	0.86
└ style adherence	0.95

Description

SHARED CONTEXT — BoG-this-week slide fanout. Lead author: Erik Garrison. Co-author: Andrea Guarracino. ANCHOR: paper_prep/synthesis/ABSTRACT.md. SUBSTRATE: end-to-end-report/ (Andrea 14-chapter report) + paper_prep/synthesis/CROSSWALK.md. EXISTING V1 DECK: slides/20260204_Subtelomics_overview_EG.summary.md (slide-by-slide ChatGPT extract — 240 lines, easiest entry) + slides/20260204_Subtelomics_overview_EG.pdf. TALK SLOT: 15 min. TOTAL SLIDES: 15. OUTPUT FILE: slides/v2/slide_NN_.md (NN = your slide number, slug short). FILE STRUCTURE (mandatory): ## Title (1 line) / ## Bullets (3-5, conference-style) / ## Primary figure (path if exists OR ggplot2/R generation script for any new annotation overlay; light R/ggplot2 work is OK inside agent worktree, no SBATCH) / ## Speaker notes (~150 words) / ## Time budget (target seconds matching the table) / ## Notes for synthesizer (cross-slide concerns, callbacks, what previous slide sets up). DO NOT modify v1 deck files. DO NOT touch other slide files in slides/v2/. Single output file. Single commit per task: "docs: BoG v2 slide NN — ".

THIS SLIDE: 10 — NEW: Hi-C bulk Mantel + exclusion robustness (consolidated). SUBSTRATE: end-to-end-report/report/05_hic_validation.md (688 lines). AVAILABLE: paper_prep/figures/fig3/figure_fig3.pdf (HG002 Pore-C contact matrix B/W=0.056 p=3.9e-85); paper_prep/figures/ed5/figure_ed5.pdf (multi-resolution Mantel + exclusion controls). REQUIRED: NEW slide. Lead with HG002 Pore-C contact matrix ordered by community. KEY NUMBERS: Mantel ρ = 0.66 → 0.79 after acrocentric+sex+strong exclusions (HG002); HG02148 0.152 → 0.720 dramatic; per-individual ρ up to 0.827 NA19036 at 10kb. Two-panel: bulk left, exclusions right. Bullet: "sequence similarity predicts 3D contact AND signal strengthens after confound exclusions". Time budget: 80s.

SHARED CONTEXT — BoG-this-week slide fanout. Lead author: Erik Garrison. Co-author: Andrea Guarracino. ANCHOR: paper_prep/synthesis/ABSTRACT.md. SUBSTRATE: end-to-end-report/ (Andrea 14-chapter report) + paper_prep/synthesis/CROSSWALK.md. EXISTING V1 DECK: slides/20260204_Subtelomics_overview_EG.summary.md (slide-by-slide ChatGPT extract — 240 lines, easiest entry) + slides/20260204_Subtelomics_overview_EG.pdf. TALK SLOT: 15 min. TOTAL SLIDES: 15. OUTPUT FILE: slides/v2/slide_NN_<slug>.md (NN = your slide number, slug short). FILE STRUCTURE (mandatory): ## Title (1 line) / ## Bullets (3-5, conference-style) / ## Primary figure (path if exists OR ggplot2/R generation script for any new annotation overlay; light R/ggplot2 work is OK inside agent worktree, no SBATCH) / ## Speaker notes (~150 words) / ## Time budget (target seconds matching the table) / ## Notes for synthesizer (cross-slide concerns, callbacks, what previous slide sets up). DO NOT modify v1 deck files. DO NOT touch other slide files in slides/v2/. Single output file. Single commit per task: "docs: BoG v2 slide NN — <slug>".

THIS SLIDE: 10 — NEW: Hi-C bulk Mantel + exclusion robustness (consolidated).
SUBSTRATE: end-to-end-report/report/05_hic_validation.md (688 lines).
AVAILABLE: paper_prep/figures/fig3/figure_fig3.pdf (HG002 Pore-C contact matrix B/W=0.056 p=3.9e-85); paper_prep/figures/ed5/figure_ed5.pdf (multi-resolution Mantel + exclusion controls).
REQUIRED: NEW slide. Lead with HG002 Pore-C contact matrix ordered by community. KEY NUMBERS: Mantel ρ = 0.66 → 0.79 after acrocentric+sex+strong exclusions (HG002); HG02148 0.152 → 0.720 dramatic; per-individual ρ up to 0.827 NA19036 at 10kb. Two-panel: bulk left, exclusions right. Bullet: "sequence similarity predicts 3D contact AND signal strengthens after confound exclusions". Time budget: 80s.

Depends on

done .assign-bog-v2-slide-10

Required by

Log

2026-05-06T00:34:51.630987004+00:00 Task paused
2026-05-06T00:37:42.482390530+00:00 Task published
2026-05-06T00:38:29.925524961+00:00 Lightweight assignment: agent=random-agent-3577bc75 (3577bc75), exec_mode=full, context_scope=task, reason=Documenter role (0.87 score, 39 tasks) with verify-against-code tradeoff is ideal for structured markdown slide synthesis from figures and substrate documents.
2026-05-06T00:41:29.941162434+00:00 Spawned by coordinator --executor claude --model opus
2026-05-06T00:41:38.420922986+00:00 Starting slide 10: Hi-C bulk Mantel + exclusion robustness
2026-05-06T00:44:01.315547648+00:00 Wrote slides/v2/slide_10_hic_bulk_mantel_exclusions.md — 80s slide, two-panel (Fig 3a HG002 Pore-C contact matrix + ED5b Mantel exclusion), key numbers HG002 0.66→0.79, CHM13 0.66→0.85, HG02148 0.15→0.72, NA19036 0.827 at 10kb
2026-05-06T00:44:11.507534214+00:00 Validated: slide file exists, all referenced figure paths (fig3/figure_fig3.pdf+.png, ed5/figure_ed5.pdf+.png) exist, structure matches task spec (Title/Bullets/Primary figure/Speaker notes/Time budget/Notes for synthesizer), 80s budget, NEW slide content not modifying v1 deck or other v2 slides
2026-05-06T00:44:23.256828127+00:00 Committed: bca2237 — pushed to remote
2026-05-06T00:44:32.369874422+00:00 Task pending eval (agent reported done; awaiting `.evaluate-*` to score)
2026-05-06T00:51:03.694385552+00:00 PendingEval → Done (evaluator passed; downstream unblocks)