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bog-v2-slide-09

BoG v2 slide 09 pca communities named clades keystone

Metadata

Statusdone
Assignedagent-768
Agent identity3184716484e6f0ea08bb13539daf07686ee79d440505f1fdf2de0357707034c3
Created2026-05-06T00:34:51.548295959+00:00
Started2026-05-06T00:40:25.970223791+00:00
Completed2026-05-06T00:47:01.896349529+00:00
Tagsbog-slide, bog-this-week, eval-scheduled
Eval score0.83
└ blocking impact0.85
└ completeness0.75
└ constraint fidelity0.70
└ coordination overhead0.90
└ correctness0.85
└ downstream usability0.85
└ efficiency0.90
└ intent fidelity0.88
└ style adherence0.80

Description

SHARED CONTEXT — BoG-this-week slide fanout. Lead author: Erik Garrison. Co-author: Andrea Guarracino. ANCHOR: paper_prep/synthesis/ABSTRACT.md. SUBSTRATE: end-to-end-report/ (Andrea 14-chapter report) + paper_prep/synthesis/CROSSWALK.md. EXISTING V1 DECK: slides/20260204_Subtelomics_overview_EG.summary.md (slide-by-slide ChatGPT extract — 240 lines, easiest entry) + slides/20260204_Subtelomics_overview_EG.pdf. TALK SLOT: 15 min. TOTAL SLIDES: 15. OUTPUT FILE: slides/v2/slide_NN_.md (NN = your slide number, slug short). FILE STRUCTURE (mandatory): ## Title (1 line) / ## Bullets (3-5, conference-style) / ## Primary figure (path if exists OR ggplot2/R generation script for any new annotation overlay; light R/ggplot2 work is OK inside agent worktree, no SBATCH) / ## Speaker notes (~150 words) / ## Time budget (target seconds matching the table) / ## Notes for synthesizer (cross-slide concerns, callbacks, what previous slide sets up). DO NOT modify v1 deck files. DO NOT touch other slide files in slides/v2/. Single output file. Single commit per task: "docs: BoG v2 slide NN — ".

THIS SLIDE: 09 — PCA / communities (the keystone slide; revise v1 slide 10). v1: PCA with C1-C15 community labels, interpretive annotations PARs-driven / PHRs-driven / DUX4-driven, full community-to-arm legend. REQUIRED: keep layout. CRITICAL — cross-reference each community to the abstract clade names: C1 (4q,10q) = 4q-10q DUX4; C2 (10p,18p) = 10p-18p; C6 (1q,13q,17q,19q,21q,22q) = the abstract's 22q/21q/19q/1q/13q/17q clade; C7 (13p,14p,15p,21p,22p) = acrocentric short arms; C14 (Xq,Yq) = PAR2; C15 (18q,Xp,Yp) = PAR1. Update legend with abstract-anchored labels. Highest-value talk slide. Time budget: 80s.

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