bog-v2-slide-08

BoG v2 slide 08 pca chromosome superpop combined

Metadata

Statusdone
Assignedagent-767
Agent identity3577bc75d6ed4f1947509aa5c086c91ce7c997c7806dab6bf6affac647452647
Created2026-05-06T00:34:51.442243827+00:00
Started2026-05-06T00:39:33.001622860+00:00
Completed2026-05-06T00:46:55.278560114+00:00
Tagsbog-slide, bog-this-week, eval-scheduled
Eval score0.85
└ blocking impact0.87
└ completeness0.82
└ constraint fidelity0.70
└ coordination overhead0.92
└ correctness0.88
└ downstream usability0.88
└ efficiency0.90
└ intent fidelity0.84
└ style adherence0.92

Description

SHARED CONTEXT — BoG-this-week slide fanout. Lead author: Erik Garrison. Co-author: Andrea Guarracino. ANCHOR: paper_prep/synthesis/ABSTRACT.md. SUBSTRATE: end-to-end-report/ (Andrea 14-chapter report) + paper_prep/synthesis/CROSSWALK.md. EXISTING V1 DECK: slides/20260204_Subtelomics_overview_EG.summary.md (slide-by-slide ChatGPT extract — 240 lines, easiest entry) + slides/20260204_Subtelomics_overview_EG.pdf. TALK SLOT: 15 min. TOTAL SLIDES: 15. OUTPUT FILE: slides/v2/slide_NN_.md (NN = your slide number, slug short). FILE STRUCTURE (mandatory): ## Title (1 line) / ## Bullets (3-5, conference-style) / ## Primary figure (path if exists OR ggplot2/R generation script for any new annotation overlay; light R/ggplot2 work is OK inside agent worktree, no SBATCH) / ## Speaker notes (~150 words) / ## Time budget (target seconds matching the table) / ## Notes for synthesizer (cross-slide concerns, callbacks, what previous slide sets up). DO NOT modify v1 deck files. DO NOT touch other slide files in slides/v2/. Single output file. Single commit per task: "docs: BoG v2 slide NN — ".

THIS SLIDE: 08 — PCA colored by chromosome AND superpopulation (combine v1 slides 8 + 9 — same plot, two colorings, side-by-side or two-panel). v1 slide 8: PCA scatter colored by chromosome, p/q shape, dim 1 16.05% / dim 2 11.2%. v1 slide 9: same PCA, recolored by AFR/AMR/EAS/EUR/SAS — mixed clusters. CRITICAL CHECK: per CROSSWALK §3 C6, repo has MDS/PCoA + UMAP but NO explicit PCA. v1 may be MDS mislabeled as PCA. Verify by checking the data files referenced (hprcv2.1Mb.subtelo.full_mds.rds vs any pca file). RECOMMEND in Notes for synthesizer: (a) confirm IS PCA → keep, or (b) IS MDS → relabel "MDS / PCoA on Jaccard distance" and flag for abstract C6 wording fix. ADD callout: "population structure is real but secondary to arm-community structure". Cross-reference Hudson Fst out-of-Africa tree (CROSSWALK §1 ch.04 + ch.12: AFR/non-AFR Fst 0.10-0.15). Time budget: 70s.

Depends on

Required by

Log