survey-hi-c

Survey: Hi-C/Pore-C 3D validation

Metadata

Statusdone
Assignedagent-636
Agent identity3577bc75d6ed4f1947509aa5c086c91ce7c997c7806dab6bf6affac647452647
Created2026-05-04T22:44:42.060054172+00:00
Started2026-05-04T22:48:13.074021028+00:00
Completed2026-05-04T23:16:05.003357538+00:00
Tagspaper-prep,survey, eval-scheduled
Tokens98144 in / 9 out
Eval score0.79
└ blocking impact0.70
└ completeness0.88
└ coordination overhead0.65
└ correctness0.85
└ downstream usability0.80
└ efficiency0.70
└ intent fidelity0.74
└ style adherence0.75

Description

INPUT: end-to-end-report/report/05_hic_validation.md (read fully). CONTEXT: Nature manuscript + 15-min talk on subtelomeric sequence sharing across HPRCv2; this task surveys ONE section. Hi-C validation includes: B/W ratio, Mantel test, ARI, multi-resolution (5kb–100kb), no-acrocentric control, O/E normalization, RPE-1. TASK: Extract: (1) Key findings with metrics (test statistics, p-values, ARI scores, B/W ratios); (2) Existing figures referenced (paths); (3) Existing CSVs/data files (paths); (4) Methods used; (5) Gaps; (6) Suggested figures main+SI with captions (produced-vs-todo); (7) Talk slide takeaways. OUTPUT: paper_prep/surveys/SURVEY_05_hic_validation.md (7 numbered sections). ACCEPTANCE: File exists, all 7 sections present, concrete paths cited.

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