fig5-2kb-direct-similarity-pilot

Fig5 safer pilot: 2kb direct similarity instead of graph untangle

Metadata

Statusdone
Assignedagent-2749
Agent identity46f6237a65ec4f1002c4d3fb201dc8633638d0947c276be7008c227e1051ba5e
Created2026-06-25T16:24:29.164501347+00:00
Started2026-06-25T16:26:45.839254393+00:00
Completed2026-06-25T16:35:49.193329525+00:00
Tagseval-scheduled
Eval score0.87
└ blocking impact0.90
└ completeness0.86
└ constraint fidelity0.85
└ coordination overhead0.76
└ correctness0.89
└ downstream usability0.91
└ efficiency0.83
└ style adherence0.88

Description

Evaluate a safer non-graph alternative for whole-genome-style Fig5 support. Use 2 kb query-grid windows around the candidate and control regions, then measure target support directly by pairwise alignment / match-distance or IMPG-style similarity, avoiding seqwish/ODGI graph construction. Compare WFMASH/SweepGA-filtered evidence to direct similarity summaries in query space; report whether PAN027 chr9q and PAN028 chr9q recover chr3q support and whether PAR/acros controls behave as expected. Use Slurm for heavy compute; do not run on the head node. Produce a concise report and TSV outputs under paper_prep/_brainstorming/fig5_2kb_direct_similarity_pilot/.

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